Accutane Side Effects: The Green Bone Surprise

Several studies have investigated the relationship between accutane use and bone health, with some suggesting that there may be cause for concern. One of the primary concerns regarding accutane and bone health is its potential to decrease bone density. Isotretinoin has demonstrated efficacy in a wide range of disorders. The beneficial effects of the drug, however, are limited by its adverse effects on the bone. There are at least several adverse effects which can preclude the use of isotretinoin and teratogenicity is the most important systemic toxicity.