Selective androgen receptor modulators (sarms) are important hypertrophic molecules that pose as potential treatments for many types of myopathy and osteopathy. The aim of this study was. Preliminary evidence of target engagement and antitumor activity. This is a first in humans study that is designed to evaluate the clinical safety profile, tolerability, and pharmacokinetic (pk) characteristics of rad140 in hormone receptor positive breast cancer. Rad140 inhibited the growth of multiple in vitro and in vivo ar+/er+ bc models.
The primary objective is safety and to determine the.
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